Benutzer: Gast  Login
Titel:

Selective imaging of the angiogenic relevant integrins ?5?1 and ?v?3.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Neubauer, S; Rechenmacher, F; Beer, AJ; Curnis, F; Pohle, K; D'Alessandria, C; Wester, HJ; Reuning, U; Corti, A; Schwaiger, M; Kessler, H
Abstract:
Pattern seekers: For the two angiogenic relevant integrins ?5?1 and ?v?3, functionalized derivatives of the selective antagonists 1 and 2 could target and discriminate between tumor cells in vivo based on their different integrin patterns and also delay tumor growth in vivo. In addition, the first ?5?1-selective integrin antagonist that enables specific molecular imaging by positron emission tomography was developed.
Zeitschriftentitel:
Angew Chem Int Ed Engl
Jahr:
2013
Band / Volume:
52
Heft / Issue:
44
Seitenangaben Beitrag:
11656-9
Sprache:
eng
Volltext / DOI:
doi:10.1002/anie.201306376
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24115324
Print-ISSN:
1433-7851
TUM Einrichtung:
Frauenklinik und Poliklinik; Klinik und Poliklinik für Nuklearmedizin
 BibTeX