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Titel:

Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial.

Dokumenttyp:
journal article
Autor(en):
Lordick, Florian; Kang, Yoon-Koo; Chung, Hyun-Cheol; Salman, Pamela; Oh, Sang Cheul; Bodoky, György; Kurteva, Galina; Volovat, Constantin; Moiseyenko, Vladimir M; Gorbunova, Vera; Park, Joon Oh; Sawaki, Akira; Celik, Ilhan; Götte, Heiko; Melezínková, Helena; Moehler, Markus; Arbeitsgemeinschaft Internistische Onkologie and EXPAND Investigators; Fein, L; Troon, S; Cosolo, W; Zabernigg, A; Andel, J; van Laethem, J-L; Kalantari, H R; D'Haens, G; Sasse, A D; Hélio, P; Franke, F A; Fanelli, M F; Cout...     »
Abstract:
Patients with advanced gastric cancer have a poor prognosis and few efficacious treatment options. We aimed to assess the addition of cetuximab to capecitabine-cisplatin chemotherapy in patients with advanced gastric or gastro-oesophageal junction cancer.In our open-label, randomised phase 3 trial (EXPAND), we enrolled adults aged 18 years or older with histologically confirmed locally advanced unresectable (M0) or metastatic (M1) adenocarcinoma of the stomach or gastro-oesophageal junction. We...     »
Zeitschriftentitel:
Lancet Oncol
Jahr:
2013
Band / Volume:
14
Heft / Issue:
6
Seitenangaben Beitrag:
490-9
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23594786
Print-ISSN:
1470-2045
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik
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