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Title:

The severity of neural invasion is associated with shortened survival in colon cancer.

Document type:
Journal Article
Author(s):
Liebl, F; Demir, IE; Rosenberg, R; Boldis, A; Yildiz, E; Kujundzic, K; Kehl, T; Dischl, D; Schuster, T; Maak, M; Becker, K; Langer, R; Laschinger, M; Friess, H; Ceyhan, GO
Abstract:
Neural invasion (NI) is a histopathologic feature of colon cancer that receives little consideration. Therefore, we conducted a morphologic and functional characterization of NI in colon cancer.NI was investigated in 673 patients with colon cancer. Localization and severity of NI was determined and related to patient's prognosis and survival. The neuro-affinity of colon cancer cells (HT29, HCT-116, SW620, and DLD-1) was compared with pancreatic cancer (T3M4 and SU86.86) and rectal cancer cells (...     »
Journal title abbreviation:
Clin Cancer Res
Year:
2013
Journal volume:
19
Journal issue:
1
Pages contribution:
50-61
Language:
eng
Fulltext / DOI:
doi:10.1158/1078-0432.CCR-12-2392
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23147996
Print-ISSN:
1078-0432
TUM Institution:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie
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