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Document type:
Review
Author(s):
Juergens, Sophie; Herrmann, Wolfgang A.; Kuehn, Fritz E.
Title:
Rhenium and technetium based radiopharmaceuticals: Development and recent advances
Abstract:
The higher homologues of group 7 transition metals, namely technetium and rhenium, offer radioisotopes suitable for the application as radiopharmaceuticals. Three generations of radiopharmaceuticals have been applied so far, with two of them reaching clinical application. While the first generation does not display a target specific functionality to bind exclusively to one ( or few) targets, the second generation allows target specific binding. The synthesis, however, is more sophisticated, but...    »
Keywords:
Rhenium; Technetium; Radiopharmaceuticals; Molecular imaging; Targeting; Review
Journal title:
JOURNAL OF ORGANOMETALLIC CHEMISTRY
Year:
2014
Journal volume:
751
Month:
FEB 1
Journal issue:
SI
Pages contribution:
83-89
Language:
English
Fulltext / DOI:
doi:10.1016/j.jorganchem.2013.07.042
Publisher:
ELSEVIER SCIENCE SA
Print-ISSN:
0022-328X
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