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Titel:

Differentiated human midbrain-derived neural progenitor cells express excitatory strychnine-sensitive glycine receptors containing ?2? subunits.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Wegner, F; Kraft, R; Busse, K; Härtig, W; Ahrens, J; Leffler, A; Dengler, R; Schwarz, J
Abstract:
Human fetal midbrain-derived neural progenitor cells (NPCs) may deliver a tissue source for drug screening and regenerative cell therapy to treat Parkinson's disease. While glutamate and GABA(A) receptors play an important role in neurogenesis, the involvement of glycine receptors during human neurogenesis and dopaminergic differentiation as well as their molecular and functional characteristics in NPCs are largely unknown.Here we investigated NPCs in respect to their glycine receptor function a...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2012
Band / Volume:
7
Heft / Issue:
5
Seitenangaben Beitrag:
e36946
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0036946
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22606311
Print-ISSN:
1932-6203
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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