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Title:

Impact of anesthesia on pathophysiology and mortality following subarachnoid hemorrhage in rats.

Document type:
Journal Article
Author(s):
Hockel, K; Trabold, R; Schöller, K; Török, E; Plesnila, N
Abstract:
Anesthesia is indispensable for in vivo research but has the intrinsic potential to alter study results. The aim of the current study was to investigate the impact of three common anesthesia protocols on physiological parameters and outcome following the most common experimental model for subarachnoid hemorrhage (SAH), endovascular perforation.Sprague-Dawley rats (n = 38) were randomly assigned to (1) chloral hydrate, (2) isoflurane or (3) midazolam/medetomidine/fentanyl (MMF) anesthesia. Arteri...     »
Journal title abbreviation:
Exp Transl Stroke Med
Year:
2012
Journal volume:
4
Journal issue:
1
Pages contribution:
5
Language:
eng
Fulltext / DOI:
doi:10.1186/2040-7378-4-5
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22414527
Print-ISSN:
2040-7378
TUM Institution:
Neurochirurgische Klinik und Poliklinik
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