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Title:

The kallikrein-kinin-system in head and neck squamous cell carcinoma (HNSCC) and its role in tumour survival, invasion, migration and response to radiotherapy.

Document type:
Journal Article; Article
Author(s):
Beck, C; Piontek, G; Haug, A; Bas, M; Knopf, A; Stark, T; Mißlbeck, M; Rudelius, M; Reiter, R; Brandstetter, M; Pickhard, A
Abstract:
In this study, we investigated the role of the kallikrein-kinin-system in head and neck squamous cell carcinoma (HNSCC) and its implication on tumour survival, invasion, migration and response to radiotherapy.The expression of BKB2R was studied in a series of 180 tumour samples to determine the functional significance of BKB2R in HNSCC. Additionally, four different HNSCC cell lines were treated with an irradiation dose of 8Gy following bradykinin receptor stimulation or blockage. Tumour cell sur...     »
Journal title abbreviation:
Oral Oncol
Year:
2012
Journal volume:
48
Journal issue:
12
Pages contribution:
1208-19
Language:
eng
Fulltext / DOI:
doi:10.1016/j.oraloncology.2012.06.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22748451
Print-ISSN:
1368-8375
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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