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Title:

In vitro adipogenesis of adipose-derived stem cells in 3D fibrin matrix of low component concentration.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Peterbauer-Scherb, A; Danzer, M; Gabriel, C; van Griensven, M; Redl, H; Wolbank, S
Abstract:
This study evaluated the suitability of adipose-derived stem cells (ASCs) combined with fibrin matrix of variable composition for adipose tissue-equivalent formation in vitro. Therefore, undifferentiated ASCs were embedded in fibrin clots composed of 2 IU/ml thrombin and fibrinogen of varying concentrations (6.25, 12.5 and 25 mg/ml) and kept under control or adipogenic conditions. Fibrin-cell composites were evaluated by scanning electron microscopy, live/dead staining, lactate-dehydrogenase (LD...     »
Journal title abbreviation:
J Tissue Eng Regen Med
Year:
2012
Journal volume:
6
Journal issue:
6
Pages contribution:
434-42
Fulltext / DOI:
doi:10.1002/term.446
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21815273
Print-ISSN:
1932-6254
TUM Institution:
Klinik und Poliklinik für Unfallchirurgie
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