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Titel:

Fas death receptor signalling: roles of Bid and XIAP.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
Autor(en):
Kaufmann, T; Strasser, A; Jost, PJ
Abstract:
Fas (also called CD95 or APO-1), a member of a subgroup of the tumour necrosis factor receptor superfamily that contain an intracellular death domain, can initiate apoptosis signalling and has a critical role in the regulation of the immune system. Fas-induced apoptosis requires recruitment and activation of the initiator caspase, caspase-8 (in humans also caspase-10), within the death-inducing signalling complex. In so-called type 1 cells, proteolytic activation of effector caspases (-3 and -7)...     »
Zeitschriftentitel:
Cell Death Differ
Jahr:
2012
Band / Volume:
19
Heft / Issue:
1
Seitenangaben Beitrag:
42-50
Sprache:
eng
Volltext / DOI:
doi:10.1038/cdd.2011.121
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21959933
Print-ISSN:
1350-9047
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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