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Title:

Poloxamer synperonic F108 improves cellular transduction with lentiviral vectors.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Höfig, I; Atkinson, MJ; Mall, S; Krackhardt, AM; Thirion, C; Anastasov, N
Abstract:
Although lentiviral transduction methods are widely used, their broader application is dependent upon the optimization of lentiviral transduction efficiency for a broad range of cell types. In the present study, we focus on the evaluation of two chemical classes with respect to their ability to increase lentiviral transduction without cytotoxicity.We compared the activity of adjuvants that are already used for lentivirus delivery with that of novel adjuvants selected on the basis of their chemic...     »
Journal title abbreviation:
J Gene Med
Year:
2012
Journal volume:
14
Journal issue:
8
Pages contribution:
549-60
Language:
eng
Fulltext / DOI:
doi:10.1002/jgm.2653
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22887595
Print-ISSN:
1099-498X
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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