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Title:

Reliable and sample saving gene expression analysis approach for diagnostic tool development.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Port, M; Seidl, C; Ruf, CG; Riecke, A; Meineke, V; Abend, M
Abstract:
This work answers the question of whether it is necessary to hybridize individual instead of pooled RNA samples on microarrays for screening gene targets suitable as diagnostic tools for radiation exposure scenarios, while at the same time meeting comparable microarray quality criteria. For developing new clinical diagnostic tools, a two-stage study design was employed in five projects. At first, pooled and not individual RNA samples were hybridized on microarrays for screening purposes. Potenti...     »
Journal title abbreviation:
Health Phys
Year:
2012
Journal volume:
103
Journal issue:
2
Pages contribution:
159-68
Language:
eng
Fulltext / DOI:
doi:10.1097/HP.0b013e31824ac318
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22951474
Print-ISSN:
0017-9078
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin
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