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Titel:

A convenient route to 4-carboxy-4-anilidopiperidine esters and acids.

Dokumenttyp:
Journal Article
Autor(en):
Marton, J; Glaenzel, B; Roessler, J; Golaszewski, D; Henriksen, G
Abstract:
The route selection and development of a convenient synthesis of 4-carboxy-4-anilidopiperidines is described. Previous routes were hampered by the low yield of the target esters as well as the inability to convert the esters to the required free acids. Considerations for large-scale production led to a modified synthesis that utilised a tert-butyl ester of 4-carboxy-4-anilidopiperidines which resulted in a dramatic increase in the overall yield of the target N-propionylated- 4-anilidopiperidine-...     »
Zeitschriftentitel:
Molecules
Jahr:
2012
Band / Volume:
17
Heft / Issue:
3
Seitenangaben Beitrag:
2823-32
Sprache:
eng
Volltext / DOI:
doi:10.3390/molecules17032823
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22399137
Print-ISSN:
1420-3049
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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