Benutzer: Gast  Login
Titel:

Specific activity of cyclin-dependent kinase I is a new potential predictor of tumour recurrence in stage II colon cancer.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Zeestraten, EC; Maak, M; Shibayama, M; Schuster, T; Nitsche, U; Matsushima, T; Nakayama, S; Gohda, K; Friess, H; van de Velde, CJ; Ishihara, H; Rosenberg, R; Kuppen, PJ; Janssen, KP
Abstract:
There are no established biomarkers to identify tumour recurrence in stage II colon cancer. As shown previously, the enzymatic activity of the cyclin-dependent kinases 1 and 2 (CDK1 and CDK2) predicts outcome in breast cancer. Therefore, we investigated whether CDK activity identifies tumour recurrence in colon cancer.In all, 254 patients with completely resected (R0) UICC stage II colon cancer were analysed retrospectively from two independent cohorts from Munich (Germany) and Leiden (Netherlan...     »
Zeitschriftentitel:
Br J Cancer
Jahr:
2012
Band / Volume:
106
Heft / Issue:
1
Seitenangaben Beitrag:
133-40
Sprache:
eng
Volltext / DOI:
doi:10.1038/bjc.2011.504
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22108518
Print-ISSN:
0007-0920
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Institut für Medizinische Statistik und Epidemiologie
 BibTeX