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Title:

Tumor Classification of Six Common Cancer Types Based on Proteomic Profiling by MALDI Imaging.

Document type:
Journal Article
Author(s):
Meding, S; Nitsche, U; Balluff, B; Elsner, M; Rauser, S; Schone, C; Nipp, M; Maak, M; Feith, M; Ebert, MP; Friess, H; Langer, R; Höfler, H; Zitzelsberger, H; Rosenberg, R; Walch, A
Abstract:
In clinical diagnostics, it is of outmost importance to correctly identify the source of a metastatic tumor, especially if no apparent primary tumor is present. Tissue-based proteomics might allow correct tumor classification. As a result, we performed MALDI imaging to generate proteomic signatures for different tumors. These signatures were used to classify common cancer types. At first, a cohort comprised of tissue samples from six adenocarcinoma entities located at different organ sites (esop...     »
Journal title abbreviation:
J Proteome Res
Year:
2012
Journal volume:
11
Journal issue:
3
Pages contribution:
1996-2003
Language:
eng
Fulltext / DOI:
doi:10.1021/pr200784p
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22224404
Print-ISSN:
1535-3893
TUM Institution:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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