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Title:

In Vitro Comparison of Novel Polyurethane Aortic Valves and Homografts After Seeding and Conditioning

Author(s):
Thierfelder, N., Koenig, F., Bombien, R., Fano, C., Reichart, B., Wintermantel, E., Schmitz, C., Akra, B.
Abstract:
The aim of the study was to compare the behavior of seeded cells on synthetic and natural aortic valve scaffolds during a low-flow conditioning period. Polyurethane (group A) and aortic homograft valves (group B) were consecutively seeded with human fibroblasts (FB), and endothelial cells (EC) using a rotating seeding device. Each seeding procedure was followed by an exposure to low pulsatile flow in a dynamic bioreactor for 5 days. For further analysis, samples were taken before and after condi...     »
Keywords:
tissue engineering heart valve homograft cell conditioning bioreactor synthetic scaffold 00002480-201305000-00018
Journal title:
ASAIO Journal
Year:
2013
Journal volume:
59
Journal issue:
3
Pages contribution:
309-316 10.1097/MAT.0b013e318289b95e
Covered by:
Scopus
Reviewed:
nein
Fulltext / DOI:
doi:10.1097/MAT.0b013e318289b95e
WWW:
http://www.scopus.com/inward/record.url?eid=2-s2.0-84877763724&partnerID=40&md5=1b1ead39f75e77da29eba3376b3d3f0b
E-ISSN:
1058-2916
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