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Titel:

Biochemical pathway modeling tools for drug target detection in cancer and other complex diseases

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
A. Marin-Sanguino; SK Gupta; EO Voit; J. Vera
Abstract:
In the near future, computational tools and methods based on the mathematical modeling of biomedically relevant networks and pathways will be necessary for the design of therapeutic strategies that fight complex multifactorial diseases. Beyond the use of pharmacokinetic and pharmacodynamic approaches, we propose here the use of dynamic modeling as a tool for describing and analyzing the structure and responses of signaling, genetic and metabolic networks involved in such diseases. Specifically,...     »
Zeitschriftentitel:
Methods Enzymol
Jahr:
2011
Nachgewiesen in:
Web of Science
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi: doi:10.1016/B978-0-12-381270-4.00011-1
Status:
Erstveröffentlichung
Format:
Text
 BibTeX