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Titel:

Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy.

Dokumenttyp:
Journal Article; Review
Autor(en):
Tschöp, Matthias; Nogueiras, Ruben; Ahrén, Bo
Abstract:
Glucagon-like peptide-1 (GLP-1) receptor agonists are established pharmaceutical therapies for the treatment of type 2 diabetes and obesity. They mimic the action of GLP-1 to reduce glucose levels through stimulation of insulin secretion and inhibition of glucagon secretion. They also reduce body weight by inducing satiety through central actions. The GLP-1 receptor agonists used clinically are based on exendin-4 and native GLP-1 and are available as formulations for daily or weekly s.c. or oral...     »
Zeitschriftentitel:
Diabetologia
Jahr:
2023
Band / Volume:
66
Heft / Issue:
10
Seitenangaben Beitrag:
1796-1808
Volltext / DOI:
doi:10.1007/s00125-023-05929-0
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37209227
Print-ISSN:
0012-186X
TUM Einrichtung:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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