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Title:

Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy.

Document type:
Journal Article; Review
Author(s):
Tschöp, Matthias; Nogueiras, Ruben; Ahrén, Bo
Abstract:
Glucagon-like peptide-1 (GLP-1) receptor agonists are established pharmaceutical therapies for the treatment of type 2 diabetes and obesity. They mimic the action of GLP-1 to reduce glucose levels through stimulation of insulin secretion and inhibition of glucagon secretion. They also reduce body weight by inducing satiety through central actions. The GLP-1 receptor agonists used clinically are based on exendin-4 and native GLP-1 and are available as formulations for daily or weekly s.c. or oral...     »
Journal title abbreviation:
Diabetologia
Year:
2023
Journal volume:
66
Journal issue:
10
Pages contribution:
1796-1808
Fulltext / DOI:
doi:10.1007/s00125-023-05929-0
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37209227
Print-ISSN:
0012-186X
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)
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