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Titel:

Pharmacological estrogen administration causes a FSH-independent osteo-anabolic effect requiring ER alpha in osteoblasts.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Seitz, S; Keller, J; Schilling, AF; Jeschke, A; Marshall, RP; Stride, BD; Wintermantel, T; Beil, FT; Amling, M; Schütz, G; Tuckermann, J; Schinke, T
Abstract:
Postmenopausal osteoporosis is characterized by declining estrogen levels, and estrogen replacement therapy has been proven beneficial for preventing bone loss in affected women. While the physiological functions of estrogen in bone, primarily the inhibition of bone resorption, have been studied extensively, the effects of pharmacological estrogen administration are still poorly characterized. Since elevated levels of follicle-stimulating hormone (FSH) have been suggested to be involved in postm...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2012
Band / Volume:
7
Heft / Issue:
11
Seitenangaben Beitrag:
e50301
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0050301
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23209701
Print-ISSN:
1932-6203
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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