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Title:

Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.

Document type:
Journal Article
Author(s):
Keller, J; Brink, S; Busse, B; Schilling, AF; Schinke, T; Amling, M; Lange, T
Abstract:
Bioactive bone substitute materials are a valuable alternative to autologous bone transplantations in the repair of skeletal defects. However, clinical studies have reported varying success rates for many commonly used biomaterials. While osteoblasts have traditionally been regarded as key players mediating osseointegration, increasing evidence suggests that bone-resorbing osteoclasts are of crucial importance for the longevity of applied biomaterials. As no standardized data on the resorbabilit...     »
Journal title abbreviation:
PLoS ONE
Year:
2012
Journal volume:
7
Journal issue:
10
Pages contribution:
e46757
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pone.0046757
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23071629
Print-ISSN:
1932-6203
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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