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Document type:
Journal Article; Article
Author(s):
Grimmer, T; Faust, M; Auer, F; Alexopoulos, P; Förstl, H; Henriksen, G; Perneczky, R; Sorg, C; Yousefi, BH; Drzezga, A; Kurz, A
Title:
White matter hyperintensities predict amyloid increase in Alzheimer's disease.
Abstract:
Impaired amyloid clearance probably contributes to increased amyloid deposition in sporadic Alzheimer's disease (AD). Diminished perivascular drainage due to cerebral small-vessel disease (CSVD) has been proposed as a cause of reduced amyloid clearance. White matter hyperintensities (WMHs) are considered to reflect CSVD and can be measured using fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI). Amyloid deposition can be determined in vivo using Pittsburgh compound B (...     »
Journal title abbreviation:
Neurobiol Aging
Year:
2012
Journal volume:
33
Journal issue:
12
Pages contribution:
2766-73
Language:
eng
Fulltext / DOI:
doi:10.1016/j.neurobiolaging.2012.01.016
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22410648
Print-ISSN:
0197-4580
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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