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Title:

White matter structure and symptom dimensions in obsessive-compulsive disorder.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Koch, K; Wagner, G; Schachtzabel, C; Schultz, CC; Straube, T; Güllmar, D; Reichenbach, JR; Peikert, G; Sauer, H; Schlösser, RG
Abstract:
There is evidence that the different symptom dimensions in obsessive-compulsive disorder (OCD) may be mediated by partially distinct neural systems. This DTI study investigated the relationship between symptom dimensions and white matter microstructure. Fractional anisotropy (FA), axial and radial diffusivity was analyzed in relation to the main OCD symptom dimensions. Symptom severity on the obsessing dimension was negatively correlated with FA in the corpus callosum and the cingulate bundle. S...     »
Journal title abbreviation:
J Psychiatr Res
Year:
2012
Journal volume:
46
Journal issue:
2
Pages contribution:
264-70
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jpsychires.2011.10.016
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22099866
Print-ISSN:
0022-3956
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer)
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