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Title:

Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial.

Document type:
journal article
Author(s):
Easton, JD; Lopes, RD; Bahit, MC; Wojdyla, DM; Granger, CB; Wallentin, L; Alings, M; Goto, S; Lewis, BS; Rosenqvist, M; Hanna, M; Mohan, P; Alexander, JH; Diener, HC; ARISTOTLE Committees and Investigators; Granger, CB; Wallentin, L; Alexander, JH; Ansell, J; Diaz, R; Easton, JD; Gersh, BJ; Hanna, M; Horowitz, J; Hylek, EM; McMurray, JJ; Mohan, P; Verheugt, FW; Diaz, R; Bahit, MC; Aylward, P; Amerena, J; Huber, K; Bartunek, J; Avezum, A; Ezekowitz, JA; Dorian, P; Lanas, F; Lisheng, L; Zhu, J; Is...     »
Abstract:
In the ARISTOTLE trial, the rate of stroke or systemic embolism was reduced by apixaban compared with warfarin in patients with atrial fibrillation (AF). Patients with AF and previous stroke or transient ischaemic attack (TIA) have a high risk of stroke. We therefore aimed to assess the efficacy and safety of apixaban compared with warfarin in prespecified subgroups of patients with and without previous stroke or TIA.Between Dec 19, 2006, and April 2, 2010, patients were enrolled in the ARISTOTL...     »
Journal title abbreviation:
Lancet Neurol
Year:
2012
Journal volume:
11
Journal issue:
6
Pages contribution:
503-11
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22572202
Print-ISSN:
1474-4422
TUM Institution:
Neurologische Klinik und Poliklinik
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