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Titel:

Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial.

Dokumenttyp:
journal article
Autor(en):
Easton, JD; Lopes, RD; Bahit, MC; Wojdyla, DM; Granger, CB; Wallentin, L; Alings, M; Goto, S; Lewis, BS; Rosenqvist, M; Hanna, M; Mohan, P; Alexander, JH; Diener, HC; ARISTOTLE Committees and Investigators; Granger, CB; Wallentin, L; Alexander, JH; Ansell, J; Diaz, R; Easton, JD; Gersh, BJ; Hanna, M; Horowitz, J; Hylek, EM; McMurray, JJ; Mohan, P; Verheugt, FW; Diaz, R; Bahit, MC; Aylward, P; Amerena, J; Huber, K; Bartunek, J; Avezum, A; Ezekowitz, JA; Dorian, P; Lanas, F; Lisheng, L; Zhu, J; Is...     »
Abstract:
In the ARISTOTLE trial, the rate of stroke or systemic embolism was reduced by apixaban compared with warfarin in patients with atrial fibrillation (AF). Patients with AF and previous stroke or transient ischaemic attack (TIA) have a high risk of stroke. We therefore aimed to assess the efficacy and safety of apixaban compared with warfarin in prespecified subgroups of patients with and without previous stroke or TIA.Between Dec 19, 2006, and April 2, 2010, patients were enrolled in the ARISTOTL...     »
Zeitschriftentitel:
Lancet Neurol
Jahr:
2012
Band / Volume:
11
Heft / Issue:
6
Seitenangaben Beitrag:
503-11
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22572202
Print-ISSN:
1474-4422
TUM Einrichtung:
Neurologische Klinik und Poliklinik
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