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Titel:

Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection.

Dokumenttyp:
Journal Article; Article
Autor(en):
Fischer, J; Bohm, S; Scholz, M; Müller, T; Witt, H; George, J; Sarrazin, C; Susser, S; Schott, E; Suppiah, V; Booth, DR; Stewart, GJ; Van Bömmel, F; Brodzinski, A; Fülöp, B; Migaud, P; Berg, T
Abstract:
In patients with chronic hepatitis C virus (HCV) infection, several variants of the interleukin-28B (IL28B) gene have been shown to correlate significantly with a sustained virologic response (SVR). Recent evidence shows that determination of one single IL28B polymorphism, rs12979860, is sufficient for predicting treatment outcome. We examined whether the combined determination of the IL28B single-nucleotide polymorphisms (SNPs), rs12979860, rs8099917, rs12980275, and rs8103142, might improve th...     »
Zeitschriftentitel:
Hepatology
Jahr:
2012
Band / Volume:
55
Heft / Issue:
6
Seitenangaben Beitrag:
1700-10
Sprache:
eng
Volltext / DOI:
doi:10.1002/hep.25582
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22234924
Print-ISSN:
0270-9139
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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