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Title:

Magnetic field-controlled gene expression in encapsulated cells.

Document type:
Journal Article
Author(s):
Ortner, V; Kaspar, C; Halter, C; Töllner, L; Mykhaylyk, O; Walzer, J; Günzburg, WH; Dangerfield, JA; Hohenadl, C; Czerny, T
Abstract:
Cell and gene therapies have an enormous range of potential applications, but as for most other therapies, dosing is a critical issue, which makes regulated gene expression a prerequisite for advanced strategies. Several inducible expression systems have been established, which mainly rely on small molecules as inducers, such as hormones or antibiotics. The application of these inducers is difficult to control and the effects on gene regulation are slow. Here we describe a novel system for induc...     »
Journal title abbreviation:
J Control Release
Year:
2012
Journal volume:
158
Journal issue:
3
Pages contribution:
424-32
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jconrel.2011.12.006
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22197778
Print-ISSN:
0168-3659
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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