User: Guest  Login
Title:

A nebulized gelatin nanoparticle-based CpG formulation is effective in immunotherapy of allergic horses.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Klier, J; Fuchs, S; May, A; Schillinger, U; Plank, C; Winter, G; Gehlen, H; Coester, C
Abstract:
In the recent years, nanotechnology has boosted the development of potential drug delivery systems and material engineering on nanoscale basis in order to increase drug specificity and reduce side effects. A potential delivery system for immunostimulating agents such as cytosine-phosphate-guanine-oligodeoxynucleotides (CpG-ODN) needs to be developed to maximize the efficacy of immunotherapy against hypersensitivity. In this study, an aerosol formulation of biodegradable, biocompatible and nontox...     »
Journal title abbreviation:
Pharm Res
Year:
2012
Journal volume:
29
Journal issue:
6
Pages contribution:
1650-7
Language:
eng
Fulltext / DOI:
doi:10.1007/s11095-012-0686-8
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22302522
Print-ISSN:
0724-8741
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
 BibTeX