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Titel:

The use of non-viral gene vectors for bioactive poly-(D,L-lactide) implant surfaces in bone tissue engineering.

Dokumenttyp:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Reckhenrich, AK; Koch, C; Egana, JT; Plank, C
Abstract:
The application of scaffolds in bone tissue engineering often comes along with side effects such as poor integrity, low regeneration rates of bone tissue with inadequate functionality, and, in case of non-degradable implants, the necessity of a second removal surgery after therapy. In this study, we coated a bioresorbable FDA-approved poly-(?-caprolactone)-scaffold for bone regeneration with a poly-(D,L-lactide) layer containing copolymer-protected gene vectors to locally provide bone morphogene...     »
Zeitschriftentitel:
Eur Cell Mater
Jahr:
2012
Band / Volume:
23
Seitenangaben Beitrag:
441-8
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/22736203
Print-ISSN:
1473-2262
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung; Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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