The motions of the phospholipid dimyristoylphosphatidylcholine (DMPC) were studied with quasi-elastic neutron scattering (QENS) on a pico- to nanosecond time scale. It was possible to evaluate these data with a model of flow-like motions of the molecules. In comparison with other liquids, it can be seen that these collective flows are not a special feature of the phospholipids but rather a common phenomenon in dense systems. The influence of some representative additives like cholesterol or sodium glycocholate on the dynamics of the phospholipid molecules was studied, as well. Cholesterol, important in nature, had a slowing down effect. In contrast, the mobility of the phospholipid molecules was enhanced in the systems containing sodium glycocholate. Also in DMPC stabilized emulsions, a pharmaceutically relevant system, the dynamics of the phospholipid was measured to be enhanced.
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The motions of the phospholipid dimyristoylphosphatidylcholine (DMPC) were studied with quasi-elastic neutron scattering (QENS) on a pico- to nanosecond time scale. It was possible to evaluate these data with a model of flow-like motions of the molecules. In comparison with other liquids, it can be seen that these collective flows are not a special feature of the phospholipids but rather a common phenomenon in dense systems. The influence of some representative additives like cholesterol or sodi...
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