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Title:

Structural polymorphism in heterogeneous cytoskeletal networks

Document type:
Zeitschriftenaufsatz
Author(s):
Lieleg, O.; Schmoller, K.M.; Cyron, C.J.; Luan, Y.; Wall, W.A.; Bausch, A.R.
Abstract:
The viscoelastic response of living cells is determined by heterogenous networks of crosslinked and bundled actin filaments. The quantitative impact of such local network heterogeneities is studied best in well-defined in vitro model systems by employing microscopic and micromechanical techniques. In this study, we show that reconstituted ?-actinin/actin networks exhibit a structural polymorphism, which is dictated by two types of mesoscopic heterogeneities. We investigate the correlation of the...     »
Keywords:
actin cytoskeleton, heterogeneities, mechanical properties
Dewey Decimal Classification:
620 Ingenieurwissenschaften
Journal title:
Soft Matter
Year:
2009
Journal volume:
5
Pages contribution:
1796-1803
Reviewed:
ja
Language:
de
Fulltext / DOI:
doi:10.1039/b814555p
Status:
Verlagsversion / published
Semester:
WS 08-09
Format:
Text
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