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Titel:

Toward a disruptive, minimally invasive small finger joint implant concept: Cellular and molecular interactions with materials in vivo

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Ben Amara, Heithem; Farjam, Pardis; Lutz, Theresa M.; Omar, Omar; Palmquist, Anders; Lieleg, Oliver; Browne, Martin; Taylor, Andy; Verkerke, Gijsbertus J.; Rouwkema, Jeroen; Thomsen, Peter
Abstract:
Osteoarthritis (OA) poses significant therapeutic challenges, particularly OA that affects the hand. Currently available treatment strategies are often limited in terms of their efficacy in managing pain, regulating invasiveness, and restoring joint function. The APRICOTⓇ implant system developed by Aurora Medical Ltd (Chichester, UK) introduces a minimally invasive, bone-conserving approach for treating hand OA (https://apricot-project.eu/). By utilizing polycarbonate urethane (PCU), this impla...     »
Stichworte:
Animal models; Biocompatibility; Gene expression; Osteoarthritis; Polyurethanes
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
Acta Biomaterialia
Jahr:
2024
Band / Volume:
183
Seitenangaben Beitrag:
130-145
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1016/j.actbio.2024.05.042
WWW:
https://www.sciencedirect.com/science/article/pii/S1742706124002897
Verlag / Institution:
Elsevier BV
E-ISSN:
1742-7061
Status:
Verlagsversion / published
Publikationsdatum:
01.07.2024
Semester:
SS 24
TUM Einrichtung:
Fachgebiet für Biomechanik, MW
Format:
Bild/Text
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