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Titel:

EMMPRIN regulates the canonical Wnt/beta-catenin signaling pathway, a potential role in accelerating lung tumorigenesis.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural
Autor(en):
Sidhu, SS; Nawroth, R; Retz, M; Lemjabbar-Alaoui, H; Dasari, V; Basbaum, C
Abstract:
Advances in the field of tumor biology have identified that tumor cells co-opt developmental signaling pathways of embryonic stem cells and thus gain the ability to proliferate, differentiate and alter cell-cell interactions. One such pathway is the Wnt/beta-catenin signaling pathway. High levels of EMMPRIN expression have been shown to correlate with poor prognosis and metastasis in a broad range of tumors. Although a variety of functions are attributed to EMMPRIN in tumorigenesis, the specific...     »
Zeitschriftentitel:
Oncogene
Jahr:
2010
Band / Volume:
29
Heft / Issue:
29
Seitenangaben Beitrag:
4145-56
Sprache:
eng
Volltext / DOI:
doi:10.1038/onc.2010.166
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20514014
Print-ISSN:
0950-9232
TUM Einrichtung:
Urologische Klinik und Poliklinik
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