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Title:

Should we treat depression with drugs or psychological interventions? A reply to Ioannidis.

Document type:
Comment; Journal Article
Author(s):
Davis, JM; Giakas, WJ; Qu, J; Prasad, P; Leucht, S
Abstract:
We reply to the Ioannidis's paper "Effectiveness of antidepressants; an evidence based myth constructed from a thousand controlled trials." We disagree that antidepressants have no greater efficacy than placebo. We present the efficacy from hundreds of trials in terms of the percentage of patients with a substantial clinical response (a 50% improvement or more symptomatic reduction). This meta-analysis finds that 42-70% of depressed patients improve with drug and 21%-39% improve with placebo. T...     »
Journal title abbreviation:
Philos Ethics Humanit Med
Year:
2011
Journal volume:
6
Pages contribution:
8
Language:
eng
Fulltext / DOI:
doi:10.1186/1747-5341-6-8
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21569244
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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