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Title:

Influence of brain-derived neurotrophic factor and apolipoprotein E genetic variants on hemispheric and lateral ventricular volume of young healthy adults.

Document type:
Journal Article; Article
Author(s):
Sidiropoulos, C; Jafari-Khouzani, K; Soltanian-Zadeh, H; Mitsias, P; Alexopoulos, P; Richter-Schmidinger, T; Reichel, M; Lewczuk, P; Doerfler, A; Kornhuber, J
Abstract:
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) and apolipoprotein E (ApoE) are thought to be implicated in a variety of neuronal processes, including cell growth, resilience to noxious stimuli and synaptic plasticity. A Val to Met substitution at codon 66 in the BDNF protein has been associated with a variety of neuropsychiatric conditions. The ApoE4 allele is considered a risk factor for late-onset Alzheimer's disease, but its effects on young adults are less clear. We sought to investigat...     »
Journal title abbreviation:
Acta Neuropsychiatr
Year:
2011
Journal volume:
23
Journal issue:
3
Pages contribution:
132-138
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1601-5215.2011.00546.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21701702
Print-ISSN:
0924-2708
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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