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Title:

Grey-matter atrophy in Alzheimer's disease is asymmetric but not lateralized.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Derflinger, S; Sorg, C; Gaser, C; Myers, N; Arsic, M; Kurz, A; Zimmer, C; Wohlschläger, A; Muhlau, M
Abstract:
In Alzheimer's disease (AD), brain atrophy has been proposed to be left lateralized. Here, we reinvestigated the asymmetry and lateralization (i.e., asymmetry directed toward one hemisphere) of grey-matter (GM) distribution in 35 patients with AD, 24 patients with amnestic mild cognitive impairment (aMCI, a state of increased risk for AD), and 30 age-matched healthy controls (HC). We analyzed GM distribution by applying voxel-based morphometry (VBM) including analyses for asymmetry and lateraliz...     »
Journal title abbreviation:
J Alzheimers Dis
Year:
2011
Journal volume:
25
Journal issue:
2
Pages contribution:
347-57
Language:
eng
Fulltext / DOI:
doi:10.3233/JAD-2011-110041
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21422522
Print-ISSN:
1387-2877
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für Psychiatrie und Psychotherapie; Neurologische Klinik und Poliklinik
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