mediaTUM
Universitätsbibliothek
Technische Universität München
User: Guest
Login
de
en
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
All data
Titel
Autor
Jahr
Less Searchfields
Reset
Search
Simple search
mediaTUM Content
University Bibliography
Electronic Examination Papers
Open Access Publikationen
Research Data
TUM.University Press
Collections
Projects
Institutions
Research Centers
TUM Board of Management
Functional Units
Partnerschaftliche Einrichtungen
Schools
TUM School of Computation, Information and Technology
(45586)
TUM School of Engineering and Design
Center of Life and Food Sciences Weihenstephan
TUM School of Management
TUM School of Medicine and Health
Deanery
(6)
Examination Papers
(6017)
Departments
(47776)
2012
(29)
2013
(23)
2014
(25)
2015
(18)
2016
(9)
2017
(12)
2018
(6)
2019
(17)
2020
(25)
2021
(25)
2022
(37)
2023
(3)
Clinical Medicine
(37131)
Institute of General Medicine (Prof. Schneider)
(322)
Institute of Radiology (Prof. Makowski)
(3542)
Institute of Experimental Hematology (Prof. Schmidt-Supprian)
(51)
Institute of Experimental Neuroimmunology (Prof. Korn)
(1)
Institute of Exerimentelle Tumortherapie (Prof. Saur)
(140)
Institute of Human Genetics (Prof. Winkelmann)
(1155)
Institute of AI and Informatics in Medicine (Prof. Rückert)
(1752)
Institute of Clinical Chemistry and Pathobiochemistry (Prof. Ruland)
(452)
Institute of Molecular Allergology (Prof. Schmidt-Weber)
(692)
Institute of Molecular Immunology (Prof. Knolle)
(139)
Institute of Molecular Oncology and Functional Genomics (Prof. Rad)
(136)
Department of Anesthesiology and Intensive Care (Prof. Schneider)
(828)
Clinic of Nutritional Medicine (Prof. Hauner)
(629)
Department of Ophthalmology
(357)
Department of Surgery (Prof. Friess)
(1707)
Department of Dermatology and Allergology (Prof. Biedermann)
(2203)
Department of Gynecology (Prof. Kiechle)
(1533)
Department of Otolaryngology (Prof. Wollenberg)
(629)
Department of Internal Medicine I - Cardiology (Prof. Laugwitz)
(1605)
Department of Internal Medicine II - Gastroenterology (Prof. Schmid)
(2477)
Department of Internal Medicine III - Hematology and Medical Oncology (Prof. Bassermann)
(1413)
Department of Pediatric Medicine (Prof. Hauer)
(1103)
Department of Oral and Maxillofacial Surgery (Prof. Wolff)
(483)
Clinic and Polyclinic for Neonatology (Prof. Peters komm.)
(6)
Department of Neurosurgery (Prof. Meyer)
(762)
Department of Neurology (Prof. Hemmer)
(2488)
2024
(20)
Associate Professorship of Human Pain Research (Prof. Ploner)
(16)
Center for Global Health
(11)
2023
(115)
2022
(145)
2021
(155)
2020
(159)
2019
(144)
2018
(116)
2017
(146)
2016
(165)
2015
(150)
2014
(150)
2013
(128)
2012
(149)
2011
(153)
2010
(102)
2009
(125)
2008
(134)
2007
(55)
2006
(31)
2005
(39)
2004
(34)
2003
(23)
2002
(3)
2001
(2)
2000
(1)
1999
(1)
1997
(1)
1996
(2)
1995
(1)
1993
(1)
Department of Nuclear Medicine (Prof. Weber)
(1891)
Department of Orthopedics and Sports Orthopedics (Prof. von Eisenhart-Rothe)
(1005)
Department of Plastic Surgery and Hand Surgery (Prof. Machens)
(473)
Department of Psychiatry and Psychotherapy (Prof. Priller)
(1872)
Department of Psychosomatic Medicine and Psychotherapy (Prof. Henningsen)
(1065)
Department of Radiooncology and Radiation Therapy (Prof. Combs)
(1613)
Department of Trauma Surgery (Prof. Biberthaler)
(780)
Department of Urology (Prof. Gschwend)
(1073)
Clinic and Polyclinic for Vascular and Endovascular Surgery (Prof. Eckstein)
(693)
German Heart Centre Munich
(3188)
Department of Preventive Sports Medicine and Sports Cardiology (Prof. Halle)
(517)
Weitere Lehrstühle und Professuren Clinical Medicine
(181)
Health and Sport Sciences
Preclinical Medicine
(5432)
Interdisziplinäres Zentrum für Zelltherapie
Roman Herzog Comprehensive Cancer Center
(206)
School Office
Zentrum für Präklinische Forschung
Ehemalige Einrichtungen
(2180)
TUM School of Natural Sciences
(14655)
TUM School of Social Sciences and Technology
(9048)
TUM Campus Straubing für Biotechnologie und Nachhaltigkeit
Service Facilities
TUM Institute for LifeLong Learning
Central Administration
mediaTUM Gesamtbestand
Einrichtungen
Schools
TUM School of Medicine and Health
Departments
Clinical Medicine
Klinik und Poliklinik für Neurologie (Prof. Hemmer)
2011
Back
Back to start of result list
Permanent link for displayed object
Title:
More CLEC16A gene variants associated with multiple sclerosis.
Document type:
Journal Article
Author(s):
Nischwitz, S; Cepok, S; Kroner, A; Wolf, C; Knop, M; Muller-Sarnowski, F; Pfister, H; Rieckmann, P; Hemmer, B; Ising, M; Uhr, M; Bettecken, T; Holsboer, F; Müller-Myhsok, B; Weber, F
Abstract:
Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Müller-Sarnowski F, Pfister H, Rieckmann P, Hemmer B, Ising M, Uhr M, Bettecken T, Holsboer F, Müller-Myhsok B, Weber F. More CLEC16A gene variants associated with multiple sclerosis. Acta Neurol Scand: 2011: 123: 400-406. © 2010 John Wiley & Sons A/S. Objectives - Recently, associations of several single-nucleotide polymorphisms (SNPs) within the CLEC16A gene with multiple sclerosis (MS), type-I diabetes, and primary adrenal insufficiency were reported. Methods - We performed linkage disequilibrium (LD) fine mapping with 31 SNPs from this gene, searching for the region of highest association with MS in a German sample consisting of 603 patients and 825 controls. Results - Four SNPs located in intron 19 of the CLEC16A gene were found associated. We could replicate the finding for SNP rs725613 and were able to show for the first time the association of rs2041670, rs2080272 and rs998592 with MS. Conclusion - All described base polymorphisms are mapping to one LD block of approximately 50 kb within intron 19 of the CLEC16A gene, suggesting a pivotal role of this region for susceptibility of MS and possibly also for other autoimmune diseases.
Journal title abbreviation:
Acta Neurol Scand
Year:
2011
Journal volume:
123
Journal issue:
6
Pages contribution:
400-6
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1600-0404.2010.01421.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20849399
Print-ISSN:
0001-6314
TUM Institution:
Neurologische Klinik und Poliklinik
BibTeX
Occurrences:
mediaTUM Gesamtbestand
Einrichtungen
Schools
TUM School of Medicine and Health
Departments
Clinical Medicine
Klinik und Poliklinik für Neurologie (Prof. Hemmer)
2011