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Titel:

Acyclovir resistance in herpes simplex encephalitis.

Dokumenttyp:
Case Reports; Journal Article; Article
Autor(en):
Schulte, EC; Sauerbrei, A; Hoffmann, D; Zimmer, C; Hemmer, B; Muhlau, M
Abstract:
Herpes simplex virus type 1 is a common cause of severe sporadic encephalitis. Treatment with acyclovir is highly effective in this disease. We report the case of a 27-year-old, immunocompetent woman with acyclovir-resistant herpes simplex encephalitis. Although she had not been treated before, herpes simplex virus type 1 DNA from the cerebrospinal fluid showed a non-synonymous mutation in the thymidine kinase gene, which is likely to have caused resistance to acyclovir. Herpes simplex encephali...     »
Zeitschriftentitel:
Ann Neurol
Jahr:
2010
Band / Volume:
67
Heft / Issue:
6
Seitenangaben Beitrag:
830-3
Sprache:
eng
Volltext / DOI:
doi:10.1002/ana.21979
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20517946
Print-ISSN:
0364-5134
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Neurologische Klinik und Poliklinik
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