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Title:

Determination of the brain-blood partition coefficient for water in mice using MRI.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Leithner, C; Müller, S; Füchtemeier, M; Lindauer, U; Dirnagl, U; Royl, G
Abstract:
Cerebral blood flow (CBF) quantification is a valuable tool in stroke research. Mice are of special interest because of the potential of genetic engineering. Magnetic resonance imaging (MRI) provides repetitive, noninvasive CBF quantification. Many MRI techniques require the knowledge of the brain-blood partition coefficient (BBPC) for water. Adopting an MRI protocol described by Roberts et al (1996) in humans, we determined the BBPC for water in 129S6/SvEv mice from proton density measurements...     »
Journal title abbreviation:
J Cereb Blood Flow Metab
Year:
2010
Journal volume:
30
Journal issue:
11
Pages contribution:
1821-4
Language:
eng
Fulltext / DOI:
doi:10.1038/jcbfm.2010.160
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20842161
Print-ISSN:
0271-678X
TUM Institution:
Neurochirurgische Klinik und Poliklinik
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