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Titel:

Determination of the brain-blood partition coefficient for water in mice using MRI.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Leithner, C; Müller, S; Füchtemeier, M; Lindauer, U; Dirnagl, U; Royl, G
Abstract:
Cerebral blood flow (CBF) quantification is a valuable tool in stroke research. Mice are of special interest because of the potential of genetic engineering. Magnetic resonance imaging (MRI) provides repetitive, noninvasive CBF quantification. Many MRI techniques require the knowledge of the brain-blood partition coefficient (BBPC) for water. Adopting an MRI protocol described by Roberts et al (1996) in humans, we determined the BBPC for water in 129S6/SvEv mice from proton density measurements...     »
Zeitschriftentitel:
J Cereb Blood Flow Metab
Jahr:
2010
Band / Volume:
30
Heft / Issue:
11
Seitenangaben Beitrag:
1821-4
Sprache:
eng
Volltext / DOI:
doi:10.1038/jcbfm.2010.160
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20842161
Print-ISSN:
0271-678X
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik
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