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Titel:

Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Fernández-Klett, F; Offenhauser, N; Dirnagl, U; Priller, J; Lindauer, U
Abstract:
Modern functional imaging techniques of the brain measure local hemodynamic responses evoked by neuronal activity. Capillary pericytes recently were suggested to mediate neurovascular coupling in brain slices, but their role in vivo remains unexplored. We used two-photon microscopy to study in real time pericytes and the dynamic changes of capillary diameter and blood flow in the cortex of anesthetized mice, as well as in brain slices. The thromboxane A(2) analog, 9,11-dideoxy-9?,11?-methanoepox...     »
Zeitschriftentitel:
Proc Natl Acad Sci U S A
Jahr:
2010
Band / Volume:
107
Heft / Issue:
51
Seitenangaben Beitrag:
22290-5
Sprache:
eng
Volltext / DOI:
doi:10.1073/pnas.1011321108
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21135230
Print-ISSN:
0027-8424
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik
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