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Titel:

Non-invasive surface-stripping for epifluorescence small animal imaging.

Dokumenttyp:
Journal Article
Autor(en):
Piper, S; Bahmani, P; Klohs, J; Bourayou, R; Brunecker, P; Muller, J; Harhausen, D; Lindauer, U; Dirnagl, U; Steinbrink, J; Wunder, A
Abstract:
Non-invasive near-infrared fluorescence (NIRF) imaging is a powerful tool to study pathophysiology in a wide variety of animal disease models including brain diseases. However, especially in NIRF imaging of the brain or other deeper laying target sites, background fluorescence emitted from the scalp or superficial blood vessels can impede the detection of fluorescence in deeper tissue. Here, we introduce an effective method to reduce the impact of fluorescence from superficial layers. The approa...     »
Zeitschriftentitel:
Biomed Opt Express
Jahr:
2010
Band / Volume:
1
Heft / Issue:
1
Seitenangaben Beitrag:
97-105
Sprache:
eng
Volltext / DOI:
doi:10.1364/BOE.1.000097
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21258449
Print-ISSN:
2156-7085
TUM Einrichtung:
Neurochirurgische Klinik und Poliklinik
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