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Title:

Are the point-of-care diagnostics MULTIPLATE and ROTEM valid in the setting of high concentrations of heparin and its reversal with protamine?

Document type:
Clinical Trial; Journal Article; Article
Author(s):
Gertler, R; Wiesner, G; Tassani-Prell, P; Braun, SL; Martin, K
Abstract:
To evaluate the in vitro effects of high concentrations of heparin and its reversal with protamine on routine laboratory parameters as well as on modified thromboelastogram (ROTEM; TEM International, Munich, Germany) and impedance aggregometry (MULTIPLATE; Dynabyte, Munich, Germany).An observational, nonrandomized in vitro study.A single-center, university hospital.Ten healthy volunteers.Heparinization of whole blood to levels of 2, 4, 6, and 8 IU/mL of heparin and reversal with protamine. For...     »
Journal title abbreviation:
J Cardiothorac Vasc Anesth
Year:
2011
Journal volume:
25
Journal issue:
6
Pages contribution:
981-6
Language:
eng
Fulltext / DOI:
doi:10.1053/j.jvca.2010.11.020
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21315618
Print-ISSN:
1053-0770
TUM Institution:
Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!)
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