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Title:

Advances in the prediction and natural history of type 1 diabetes.

Document type:
Journal Article; Review; Article
Author(s):
Bonifacio, E; Ziegler, AG
Abstract:
Type 1 diabetes (T1D) has the hallmark characteristics of autoimmunity superimposed on genetic susceptibility. Both genes (HLA) and immune markers (autoantibodies) have been validated as predictive markers of the subsequent development of the disease in higher-risk relatives and the lower-risk general population. Over the last three decades, using a combination of genes, immune, and metabolic markers, clinicians are now able to quantify an individual's disease risk from 1 in 100,000 to more than...     »
Journal title abbreviation:
Endocrinol Metab Clin North Am
Year:
2010
Journal volume:
39
Journal issue:
3
Pages contribution:
513-25
Language:
eng
Fulltext / DOI:
doi:10.1016/j.ecl.2010.05.007
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20723817
Print-ISSN:
0889-8529
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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