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Titel:

Curcumin attenuates oxidative stress and inflammatory response in the early phase after partial hepatectomy with simultaneous intraabdominal infection in rats.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Seehofer, D; Schirmeier, A; Bengmark, S; Cho, SY; Koch, M; Lederer, A; Rayes, N; Menger, MD; Neuhaus, P; Nüssler, AK
Abstract:
Curcumin is a nontoxic, hepatoprotective antioxidant. It has been shown to efficiently scavenge oxygen free radicals, increase intracellular glutathione concentrations, and prevent lipid peroxidation in rat hepatocytes. Moreover, it has strong anti-inflammatory effects. In the present study we assessed its effect in a model of liver regeneration impaired by bacterial infections.Male Sprague-Dawley rats underwent sham operation, cecal ligation and puncture (CLP), synchronous partial hepatectomy (...     »
Zeitschriftentitel:
J Surg Res
Jahr:
2010
Band / Volume:
159
Heft / Issue:
1
Seitenangaben Beitrag:
497-502
Volltext / DOI:
doi:10.1016/j.jss.2008.12.006
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19321178
Print-ISSN:
0022-4804
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie
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