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Titel:

Quantitative assessment of hypoxia kinetic models by a cross-study of dynamic 18F-FAZA and 15O-H2O in patients with head and neck tumors.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Shi, K; Souvatzoglou, M; Astner, ST; Vaupel, P; Nüsslin, F; Wilkens, JJ; Ziegler, SI
Abstract:
Several kinetic models have been proposed to assess the underlying oxygenation status behind hypoxia tracer uptake and have shown advantages, compared with static analysis, in discriminating hypoxic regions. However, the quantitative assessment of mathematic models that take into consideration clinical applications and their biologic nature is still challenging. We performed a feasibility study to assess hypoxia kinetic models using voxelwise cross-analysis between the uptake of the perfusion tr...     »
Zeitschriftentitel:
J Nucl Med
Jahr:
2010
Band / Volume:
51
Heft / Issue:
9
Seitenangaben Beitrag:
1386-94
Sprache:
eng
Volltext / DOI:
doi:10.2967/jnumed.109.074336
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20720045
Print-ISSN:
0161-5505
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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