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Titel:

Huge splicing frequency in human Y chromosomal UTY gene.

Dokumenttyp:
Journal Article
Autor(en):
Laaser, I; Theis, FJ; de Angelis, MH; Kolb, HJ; Adamski, J
Abstract:
Over 90% of human genes produce more than one mRNA by alternative splicing (AS). Human UTY (ubiquitously transcribed tetratricopeptide repeat protein on the chromosome Y) has six mRNA-transcripts. UTY is subject to interdisciplinary approaches such as Y chromosomal genetics or development of leukemia immunotherapy based on UTY-specific peptides. Investigating UTY expression in a normal and leukemic setting we discovered an exceptional splicing phenomenon fostering huge transcript diversity. Tran...     »
Zeitschriftentitel:
OMICS
Jahr:
2011
Band / Volume:
15
Heft / Issue:
3
Seitenangaben Beitrag:
141-54
Sprache:
eng
Volltext / DOI:
doi:10.1089/omi.2010.0107
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21329462
Print-ISSN:
1536-2310
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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