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Titel:

Transplantation of CD6-depleted peripheral blood stem cells after DLA-haploidentical bone marrow transplantation contributes to engraftment and tolerance in a preclinical model of stem cell transplantation.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Zorn, J; Schwamberger, S; Panzer, W; Adler, H; Kolb, HJ
Abstract:
Human leukocyte antigen (HLA)-haploidentical stem cell transplantation is an opportunity for nearly all patients lacking an HLA matched stem cell donor. However, graft rejection and graft-versus-host disease (GvHD) as well as infectious complications still result in high treatment-related mortality. Here, we used the dog as a preclinical model for the study of tolerance induction with the aim to optimize and to improve a clinical protocol of haploidentical stem cell transplantation. For this pur...     »
Zeitschriftentitel:
Vet Immunol Immunopathol
Jahr:
2011
Band / Volume:
144
Heft / Issue:
1-2
Seitenangaben Beitrag:
27-35
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.vetimm.2011.06.036
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21784536
Print-ISSN:
0165-2427
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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