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Title:

Antinociceptive efficacy and plasma concentrations of transdermal buprenorphine in dogs.

Document type:
Journal Article
Author(s):
Pieper, K; Schuster, T; Levionnois, O; Matis, U; Bergadano, A
Abstract:
To assess the antinociceptive efficacy of transdermal (TD) buprenorphine (B) in dogs, a prospective, positive-controlled experimental study was performed in 10 healthy Beagles. In an open label crossover design, the dogs initially received intravenous B (IVB, 0.02 mg kg(-1)) as a positive control, followed by TDB (52.5 ?g h(-1)) 4 months later. Blood was collected at regular intervals for determination of the plasma concentrations of B ([B]) and its metabolite norbuprenorphine. The antinocicepti...     »
Journal title abbreviation:
Vet J
Year:
2011
Journal volume:
187
Journal issue:
3
Pages contribution:
335-41
Language:
eng
Fulltext / DOI:
doi:10.1016/j.tvjl.2010.01.013
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20206560
Print-ISSN:
1090-0233
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie
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