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Titel:

Extracellular matrix metalloproteinase inducer (CD147) and membrane type 1-matrix metalloproteinase are expressed on tissue macrophages in calcific aortic stenosis and induce transmigration in an artificial valve model.

Dokumenttyp:
Journal Article
Autor(en):
Joghetaei, N; Akhyari, P; Rauch, BH; Cullen, P; Lichtenberg, A; Rudelius, M; Pelisek, J; Schmidt, R
Abstract:
Matrix metalloproteinases participate in remodeling of extracellular matrix, which is central to the development of aortic stenosis. Synthesis of certain matrix metalloproteinases is induced by the glycoprotein extracellular matrix metalloproteinase inducer. We investigated whether extracellular matrix metalloproteinase inducer and membrane-type 1 matrix metalloproteinase are abundant in calcific aortic valve and their role in the pathogenesis of this condition.Sixteen patients who underwent sur...     »
Zeitschriftentitel:
J Thorac Cardiovasc Surg
Jahr:
2011
Band / Volume:
142
Heft / Issue:
1
Seitenangaben Beitrag:
191-8
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jtcvs.2010.09.051
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21146836
Print-ISSN:
0022-5223
TUM Einrichtung:
Fachgebiet Gefäßchirurgie (Prof. Eckstein); I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Allgemeine Pathologie und Pathologische Anatomie
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