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Titel:

EMMPRIN (CD147/basigin) mediates platelet-monocyte interactions in vivo and augments monocyte recruitment to the vascular wall.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Schulz, C; von Brühl, ML; Barocke, V; Cullen, P; Mayer, K; Okrojek, R; Steinhart, A; Ahmad, Z; Kremmer, E; Nieswandt, B; Frampton, J; Massberg, S; Schmidt, R
Abstract:
Platelets play a central role in hemostasis, in inflammatory diseases such as atherosclerosis, and during thrombus formation following vascular injury. Thereby, platelets interact intensively with monocytes and enhance their recruitment to the vascular wall.To investigate the role of the extracellular matrix metalloproteinase inducer (EMMPRIN) in platelet-monocyte interactions.Isolated human monocytes were perfused in vitro over firmly adherent platelets to allow investigation of the role of EMM...     »
Zeitschriftentitel:
J Thromb Haemost
Jahr:
2011
Band / Volume:
9
Heft / Issue:
5
Seitenangaben Beitrag:
1007-19
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1538-7836.2011.04235.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21320284
Print-ISSN:
1538-7933
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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